Research
The Division of Gastroenterology at Washington University School of Medicine performs cutting-edge molecular and translational research.
We have a diverse research base with physician-scientists (MD and MD/PhD) and PhD scientists conducting basic investigation into the molecular regulation of development, nutrient absorption, colon carcinogenesis, immune tolerance and inflammation and repair.
In addition, we conduct a range of active translational research, including novel therapies for inflammatory bowel disease, obesity and energy metabolism, hepatic steatosis, hepatitis C and topographic manometric assessment of esophageal motility.
Learn more about our NIH-funded Digestive Diseases Research Core Center »
Principal Investigator |
Research Interests |
Matthew Ciorba, MD |
- Inflammatory bowel diseases
- Indoleamine 2,3 Dioxygenase in Intestinal Inflammation
- The role of probiotic bacteria in modulating mechanisms of intestinal repair
- Visit The Ciorba Lab Site
|
Nicholas Davidson, MD |
- The molecular genetics of lipid transport and in the post-transcriptional regulation of gene expression
- Lipid storage diseases and defects in macronutrient absorption
- The molecular genetics of colorectal cancer
|
Brian Dieckgraefe, MD, PhD |
- The study of the cellular signaling pathways and mediators used to sense and respond to epithelial injury
- The identification of proximate events in the development of Crohn’s disease
|
Dayna S. Early, MD |
- Understanding barriers to colorectal cancer screening
- The effect of insulin resistance on the development of colorectal neoplasia
- The role of selenium on the development of colorectal neoplasia
- Diagnosis of gastrointestinal cancers
|
Marc Levin, MD |
- The molecular basis of the small intestinal adaptive response following loss of small bowel surface area
- Nutrient modulation of the small intestinal adaptive response
- The role of retinoids and cellular retinol binding proteins in small intestinal adaptation
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Jason Mills, MD, PhD |
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Rodney Newberry, MD |
- Intestinal inflammatory diseases
- The incidence of celiac disease among persons with osteoporosis
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Deborah Rubin, MD |
- Identifying the molecular mechanisms underlying intestinal epithelial cell proliferation and differentiation
- The role of epithelial mesenchymal interactions in inducing the normal morphogenesis and differentiation of the gut mucosa
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William Stenson, MD |
- The role of inflammation in intestinal injury and wound repair
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Sandeep Tripathy, MD, PhD |
- Natural Killer (NK) cell development and activation
- Role of innate immunity in the pathogenesis of gastrointestinal and hepatic diseases
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