Parakkal Deepak, MBBS, MS

Parakkal Deepak, MBBS, MS

Associate Professor of Medicine
Director of Clinical and Translational Research, Division of Gastroenterology

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Education

  • IBD Fellowship: Mayo Clinic, Rochester, MN (2017)
  • Fellowship: Mayo Clinic, Rochester, MN (2016)
  • Residency: University of Chicago (NorthShore), Chicago, IL (2011)
  • Residency: All India Institute of Medical Sciences, New Delhi, India (2007)
  • MBBS: Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India (2004)

Clinical Interests

Crohn’s disease, ulcerative colitis, pouchitis, celiac disease, checkpoint inhibitor induced colitis, microscopic colitis.

My clinical expertise is in the diagnosis and management of complex IBD with the overarching focus on improving the precision of medical therapy in IBD, focusing on the right patient, the right drug and the right dose, to maximize efficacy and limit side-effects.

Research Interests

I am currently a physician-scientist in the Inflammatory Bowel Disease (IBD) Center and Director of Clinical and Translation Research for the Division of Gastroenterology. My work has been funded by the American College of Gastroenterology, the American Gastroenterological Association, and The Leona M. and Harry B. Helmsley Charitable Trust apart from investigator-initiated grants funded by industry. My group’s primary focus is on fistulizing perianal Crohn’s disease where I co-lead a bench-bedside basic-translational-clinical group focused on improving the precision of care in perianal CD through single cell work, radiomics and 3D print applications and we are part of the international TOpCLASS fistula consortium. Additional focus area of research is cardiometabolic syndrome in IBD where our group has made novel observations in prevalence of MASLD, risk of cirrhosis, performance of current ASCVD prediction tools in patients with IBD and ongoing work on GLP-1 receptor agonists in IBD. I have co-founded the REBOOT IBD consortium across 11 leading IBD centers in the United States to publish real-world data on outcomes with newest advanced therapies in IBD.  I serve as the site-PI for multicenter industry funded clinical trials in IBD and have served on the steering committee of trials. I additionally serves as the Deputy Director of Data Quality and Enhancement of the prospective longitudinal biobanking cohort, the SPARC-IBD of the Crohn’s and Colitis Foundation and on the National Scientific Advisory Committee of the Crohn’s and Colitis Foundation.